The Official Journal of the Turkish Society Of Clinical Microbiology and Infectious Diseases (KLİMİK)

Treatment

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Original Article / VOLUME 6, ISSUE 4, DECEMBER 2024

Impact of Needle-Free Connector and Prefilled Flushing Syringe Shortage on CLABSI Rates in Pediatric Intensive Care

İlker Devrim and others

The most common and serious complication of central venous catheter usage is central line–associated bloodstream infections (CLABSIs) in children and adults. Between 2011 and 2014, CLABSIs were the most frequently reported healthcare-associated illness among hospitals in the USA. Bloodstream infections associated with central lines are […] Read More

Original Article / VOLUME 6, ISSUE 4, DECEMBER 2024

Cystic Echinococcosis Cases: A Retrospective Evaluation in a General Surgery Department

Oruç Numan Gökçe and others

Cystic echinococcosis (CE), caused mainly by Echinococcus granulosus, is a parasitic disease common in Mediterranean countries such as Türkiye. Although it can occur anywhere in the body, it predominantly affects the liver. The disease is often asymptomatic; thus, cysts are often detected incidentally during imaging studies performed for other purposes. Read More

Original Article / VOLUME 6, ISSUE 3, SEPTEMBER 2024

The Efficacy of the Cognitive Exercise Therapy Approach by Telerehabilitation in People Living with HIV: Preliminary Results

Süreyya Damar-Örenler and others

Human immunodeficiency virus (HIV) remains a significant global health challenge with societal impacts. Despite a decline in the annual number of new cases worldwide, the incidence of HIV is on the rise in the Eastern Europe/Central Asia region, including Türkiye. With the introduction of new antiretroviral treatments (ARTs), HIV has transitioned from a […] Read More

Original Article / VOLUME 6, ISSUE 3, SEPTEMBER 2024

Antimicrobial Use Among Outpatients at Benjamin Mkapa Hospital in Dodoma Central Zone of Tanzania: A Prospective Descriptive Study

Kauke Bakari Zimbwe and others

Antimicrobial resistance (AMR) is declared one of humanity’s top ten global public health threats. AMR is associated with increased hospitalizations, extended hospital stays, readmissions, and a higher mortality risk. In 2019, 4.95 million deaths, including 1.27 million directly attributable, were associated with bacterial AMR. Sub-Saharan Africa has the highest all-age death rate [...] Read More

Original Article / VOLUME 6, ISSUE 3, SEPTEMBER 2024

The Efficacy of Glecaprevir/Pibrentasvir in Chronic Hepatitis C Patients and the Impact of the COVID-19 Pandemic: Multicenter Real-Life Data

Yunus Gürbüz and others

In 75-85% of cases of acute hepatitis C infection, the disease becomes chronic and carries a risk of developing liver failure and hepatocellular cancer. In its global hepatitis report published in 2017, the World Health Organization (WHO) reported that 71.1 (95% uncertainty interval [UI]: 62.1-79.0 million) million people were chronically infected with the hepatitis C virus [...] Read More

Review Article / VOLUME 6, ISSUE 2, JUNE 2024

Discontinuation of Nucleos(t)ide Analogues in HBeAg Negative Chronic Hepatitis B Patients: Risks and Benefits

Pınar Korkmaz and Neşe Demirtürk

Chronic hepatitis B (CHB) remains a major threat to global public health, affecting 296 million people worldwide. CHB increases the risk of cirrhosis, liver failure and hepatocellular carcinoma, causing liver-related morbidity and mortality. All these risks can be prevented with antiviral treatment. Although there is no curative treatment for CHB today the virus can be effectively controlled with existing (...) Read More

Original Article / VOLUME 6, ISSUE 2, JUNE 2024

The Incidence and Risk Factors of Early Periprosthetic Joint Infections

Zeynep Tekin-Taş and others

Hip and knee arthroplasties stand out as the most prevalent surgical interventions employed to address joint deformities, predominantly stemming from osteoarthritis associated with an aging population. In Turkey, a total of 34,240 hip arthroplasties and 81,109 knee arthroplasties were conducted in 2022. Meanwhile, in the United States of America (...) Read More

Original Article / VOLUME 6, ISSUE 2, JUNE 2024

Antimicrobial Susceptibility of Various MRSA Clinical Isolates and the Impact of Glycopeptide MICs on Clinical and Microbiological Outcomes

Elif M. Sarıcaoğlu and Fügen Yörük

Staphylococcus aureus, particularly methicillin-resistant Staphylococcus aureus (MRSA), is a major cause of serious hospital and community-acquired infections and is associated with increased health care costs, prolonged antibiotic treatment and hospitalization, morbidity, and mortality. While glycopeptides (...) Read More

Original Article / VOLUME 6, ISSUE 2, JUNE 2024

The Impact of Reporting the Same-Day Identification and Antibiotic Susceptibility Test Results on the Treatment of Bloodstream Infections

Mervenur Demir and others

The global increase in the rate of multi-drug resistant (MDR) bacterial infections in recent years is an important public health problem that limits the therapeutic options. The issue becomes particularly critical in cases of bloodstream infections (BSI) in which delay is associated with high mortality rates. Bacteria grown in blood cultures (BC) must be subcultured on the solid media (...) Read More

Original Article / VOLUME 6, ISSUE 1, MARCH 2024

Knowledge and Attitudes of Patients About the Rational Use of Antibiotics

Pınar Korkmaz and others

Antimicrobial resistance can lead to morbidity and mortality in serious infections. Therefore, antimicrobial resistance has been accepted as a global public health problem in the 21st century. Unnecessary and excessive use of drugs is a serious problem in our country as well as in the rest of the world. Unnecessarily used drugs play an important role (...) Read More

Original Article / VOLUME 6, ISSUE 1, MARCH 2024

Individualized High Dose Intravenous Anakinra Treatment in Cancer Patients with COVID-19 Associated Cytokine Storm: A Retrospective Controlled Study

Ramazan Çakmak and Murat Bektaş

Coronavirus disease 2019 (COVID-19) is a potentially life-threatening disease caused by SARS-CoV-2. Clinical findings of COVID-19 are ranged from asymptomatic to severe pneumoniae, acute respiratory distress syndrome, multiorgan failure and death. A severe COVID-19 course is associated with a higher inflammatory state (cytokine storm) due to the excessive release (...) Read More

Review Article / VOLUME 5, ISSUE 4, DECEMBER 2023

New Treatment Options in Chronic Hepatitis B: How Close Are We to Cure?

Pınar Korkmaz and others

Hepatitis B virus (HBV) infection is the leading cause of chronic liver disease worldwide. HBV-infected patients are at risk of developing liver cirrhosis and hepatocellular carcinoma (HCC) for life. Today, pegylated interferon (Peg-IFN) and nucleos(t)ide analogues (NAs) are used in the treatment of patients with chronic hepatitis B (CHB). Both treatment options have limitations. Read More

Review Article / VOLUME 5, ISSUE 3, SEPTEMBER 2023

COVID-19: An Update on Epidemiology, Prevention and Treatment, September-2023

Serap Şimşek-Yavuz

After the World Health Organization (WHO) declared an end to COVID-19 as a global public health emergency on May 5, 2023, we have entered a new era in the pandemic, and most countries have already returned to normal life. This declaration was resulted from the 12-month downward trend of the pandemic, increased immunity due to the highly effective vaccines, decreased death rates, and decreased pressure on once overwhelmed (...) Read More

Original Article / VOLUME 5, ISSUE 2, JUNE 2023

COVID-19 Among Patients with Psoriasis: A Single-Center Retrospective Cross-Sectional Study

Özge Kaya and others

Psoriasis, a chronic inflammatory disease, has a multifactorial etiology, including genetic, environmental, and behavioral factors. Since psoriasis is an immune system-mediated disease, immunosuppressive agents and biological treatments are frequently used in its treatment; however, these agents are known to increase the risk of infection. This situation (...) Read More

Original Article / VOLUME 4, ISSUE 4, DECEMBER 2022

Stenotrophomonas maltophilia Bacteremia: From Diagnosis to Treatment

Pınar Aysert-Yıldız and others

Stenotrophomonas maltophilia is an aerobic, non-fermentative, Gram-negative bacterium widespread in aquatic environments and soil. It has an inherent ability to adhere to abiotic surfaces and forms biofilms. It is usually considered to be a commensal and a low-grade pathogen. However, it can cause severe infections in the immunocompromised and debilitated (...) Read More

Case Report / VOLUME 2, ISSUE 1, APRIL 2020

Adverse Cardiac Events Related to Hydroxychloroquine Prophylaxis and Treatment of COVID-19

Rehile Zengin and others

Hydroxychloroquine is commonly used for the treatment of rheumatic diseases because of its antinflammatory effects. It is a 4-amino-quinoline that is widely used for the treatment purposes. The Scientific Advisory Board of Ministry of Health of Turkey for COVID-19 recommends HCQ for treatment and also for prophylactic use of COVID-19. Infectious Diseases Society of America (IDSA) suggested the HCQ but also warned Read More