The Effect of Prophylactic Carbapenem Use on Outcomes in Acute Pancreatitis: A Systematic Review and Meta-Analysis

Merve Büyükkörük and others

The incidence of acute pancreatitis ranges from 2.2-136/100,000 people and increases by 3.7% per year. Necrosis occurs in nearly 15% of acute pancreatitis. The sterile necrosis of pancreatic or peripancreatic tissue gets infected by translocation of gastrointestinal flora or peripheral spread from the skin, respiratory, or urinary tract. Mortality rates increase with infection in necrotic tissue and rise from 19.8% to 35.2% in acute pancreatitis . Read More