The Official Journal of the Turkish Society Of Clinical Microbiology and Infectious Diseases (KLİMİK)

Diagnosis and Treatment

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IDCM Newsfeed / VOLUME 1, ISSUE 1, APRIL 2019

CRISPR-Cas System: A Brief History and Future in the Diagnosis and Treatment of Infectious Diseases

Barış Otlu

The discovery of Clustered Regularly Interspaced Short Palindromic Repeat (CRISPR) and CRISPR-Associated System (Cas) have led to revolutionary advancements in almost every field of biology. The CRISPR-Cas system is part of an adaptive immune system in bacteria, and this system protects the organism from invading genetic elements of bacteriophages and (...) Read More

Original Article / VOLUME 4, ISSUE 4, DECEMBER 2022

Stenotrophomonas maltophilia Bacteremia: From Diagnosis to Treatment

Pınar Aysert-Yıldız and others

Stenotrophomonas maltophilia is an aerobic, non-fermentative, Gram-negative bacterium widespread in aquatic environments and soil. It has an inherent ability to adhere to abiotic surfaces and forms biofilms. It is usually considered to be a commensal and a low-grade pathogen. However, it can cause severe infections in the immunocompromised and debilitated (...) Read More

Case Report / VOLUME 5, ISSUE 1, MARCH 2023

Challenges in Diagnosis and Treatment of Fasciola hepatica Infection

Fatihan Pınarlık and others

Fascioliasis is a neglected tropical disease caused by liver flukes, Fasciola hepatica or Fasciola gigantica, and affects at least 2.4 million people worldwide, according to World Health Organization (WHO) estimates (1). Sheep and cattle are the natural definitive hosts of F. hepatica infection; therefore, fascioliasis is common in sheep-raising (...) Read More

Case Report / VOLUME 5, ISSUE 4, DECEMBER 2023

Clinical Entity Mimicking Infectious Cellulitis: Eosinophilic Cellulitis (Wells’ Syndrome)

Mustafa Deniz and others

Eosinophilic cellulitis (EC) is a rare inflammatory skin condition with fewer than 200 documented cases in the medical literature. There are only a limited number of case reports available from our country. The prevalence and incidence of EC are unknown. The disease is characterized by pruritic, non-purulent, erythematous plaques (...) Read More

Original Article / VOLUME 6, ISSUE 1, MARCH 2024

Predictors of Significant Histological Hepatic Abnormality in Treatment-Naive Patients Infected with HBeAg-Negative Chronic Hepatitis B

Gülşah Tunçer and others

Chronic hepatitis B (CHB)  infection is a global health problem that the World Health Organization (WHO) reported 296 million individuals diagnosed with CHB, and 820,000 died worldwide in 2019. In our country, as per the Türkiye Viral Hepatitis Prevention and Control Program for 2018-2023, there have been 3.3 million patients with CHB infection in Türkiye. Read More

Original Article / VOLUME 6, ISSUE 1, MARCH 2024

Detrimental Effects of Sterilization Types on Single-Use Coronary Angioplasty Catheters for Reuse: An Electron Microscopic Study

Tuba Kuruoğlu and others

Reprocessing a disposable medical device in which sterility deteriorates without contact with the blood and body fluids is called “reprocessing.” If it is ready for use by being processed again for the same or another patient, it is named reuse. The increasing number of blood-borne diseases led to the broader use of disposable instruments. Cardiac catheters, (...) Read More

Original Article / VOLUME 6, ISSUE 2, JUNE 2024

Prospective Clinical Follow-Up Results of Infective Endocarditis

Merve Arslan and others

Infective endocarditis is a clinical condition that affects the endocardial surface of the heart, involving natural or prosthetic heart valves and intracardiac devices.  It is a high-cost and high-mortality infectious disease with an increasing incidence and is more frequently diagnosed with advancing diagnostic methods. Along with well-defined cardiac (previous endocarditis, presence of intracardiac prosthetic materials, (...) Read More

Visual Case Presentation / VOLUME 6, ISSUE 3, SEPTEMBER 2024

Thoracic Tuberculous Spondylodiscitis with Abscess Formation

Handan Alay and others

A 78-year-old male patient with diagnoses of diabetes, hypertension, and gout presented with fever, night sweats, weight loss, and back pain for the past two months. On physical examination, he had a body temperature of 37.5°C and tenderness on palpation in the thoracolumbar region. His white blood cell (WBC) count was [...] Read More

Case Report / VOLUME 6, ISSUE 3, SEPTEMBER 2024

Primary Tuberculous Pyomyositis of the Left Forearm Muscles

Ali Mert and others

Pyomyositis is a primary infection of skeletal muscle that does not result from a contiguous disease, is hematogenous in origin, and often results in abscess formation. Although pyomyositis is classically an infection in tropical regions, it is an emerging infection in temperate climates. Pyomyositis is frequently caused by aerobic Gram-positive and Gram-negative bacteria. Read More

Case Report / VOLUME 6, ISSUE 3, SEPTEMBER 2024

Henoch-Schönlein Purpura in a Patient with AIDS: A Case Report and Literature Review

Abdurrahman Kaya and others

Henoch-Schönlein purpura (HSP) is a systemic small-vessel vasculitis characterized by involvement in the skin, kidney, and gastrointestinal system. It is frequently seen in children, accounting for 90% of cases. HSP is less common in adults. Cutaneous involvement is the most common presentation, and in some cohorts, adult HSP is more severe and has worse [...] Read More

Case Report / VOLUME 6, ISSUE 3, SEPTEMBER 2024

Late Dehiscence of Mechanical Aortic Valved Conduit and Distal Anastomotic Leakage due to Endocarditis Caused by Pseudomonas stutzeri

Mehmet Emirhan Işık and others

Infective endocarditis is the infection of the endocardial surfaces of the heart, including native valves, mural endocardium, or septal defects. Involvement of previously implanted prosthetic valves, intracardiac devices, or pacemakers are commonly predisposing risk factors for infective endocarditis. If left untreated, it is inevitably fatal due to complications such as congestive heart failure, stroke (...) Read More

Brief Report / VOLUME 6, ISSUE 3, SEPTEMBER 2024

Sandfly Virus Infection in Adana, Türkiye

Yusuf Ziya Demiroğlu and others

The hazards of sandfly viruses have been known for about 100 years. Sandfly fever viruses of the genus Phlebovirus in the Bunyaviridae family are endemic in Mediterranean, Middle Eastern, Northern African, and Western Asian countries. Sandfly viruses have been reported from Italy, Croatia, Spain, Cyprus, Iran, and Iraq. Read More

Original Article / VOLUME 6, ISSUE 3, SEPTEMBER 2024

Changes of Procalcitonin Kinetics According to Renal Clearance in Critically Ill Patients with Primary Gram-Negative Bloodstream Infections

Hasan Selçuk Özger and others

Procalcitonin (PCT) is a biomarker frequently used in the diagnosis and prognosis of infection. The lack of optimum cut-off values and the high serum PCT levels in some non-infectious conditions restrict its clinical use. Therefore, PCT use is not recommended regardless of clinical parameters. This limitation in clinical use has led to PCT kinetic evaluations rather than predictions [...] Read More

Original Article / VOLUME 6, ISSUE 3, SEPTEMBER 2024

The Relationship of Carotid and Brachial Artery Wall Thickness Measurement with Cardiovascular Risk Scoring in Individuals Living with HIV

Zeynep Bilgiç and others

The use of antiretroviral therapy (ART) in individuals with the human immunodeficiency virus (HIV) has significantly increased their life expectancy. Nevertheless, an increase in the frequency of chronic diseases such as diabetes mellitus (DM), hypertension (HT), and cardiovascular disease (CVD) in this population with advancing age is expected. Also, they are at greater […] Read More