Diagnosis and Treatment
Fatemeh Amirinia and others
β-glucans area part of the fungal cell wall structure, mainly considered a potential therapeutic and diagnostic tool for invasive fungal infections (IFIs) (1). Several studies have been conducted about their effects on health. They have been reported to reduce blood glucose and have a strong inhibitory effect on lipid peroxidation as a regulator of blood [...] Read More
Derya Kormaz and others
Central nervous system (CNS) infections can develop due to bacteria, viruses, and fungi. The most common cause is bacteria. Although fungal meningitis is rare, there has been an increase in the number of cases in recent years. In the vast majority of CNS candidiasis, the primary site of infection is the lungs or skin, followed by direct or hematogenous [...] Read More
Ayten Kadanalı and others
The prevalence of diabetes continues to increase both in our country and in the world. The International Diabetes Federation estimated that as of 2021, 537 million adults in the world were living with diabetes. In Türkiye, this number is over 9 million. This situation leads [...] Read More
Melike İnan-Hekimoğlu and others
Cytomegalovirus (CMV) is a DNA virus from the Herpesviridae family that can remain latent in the body for life after primary infection and reactivate and cause viral shedding, especially in cases of immunosuppression. In studies conducted in different patient groups from Türkiye, CMV seroprevalence was reported to be between 85-100%. CMV can affect […] Read More
Khalis Mustafayev and others
Invasive Candida infections have increased significantly in recent years due to various risk factors, including invasive procedures, vascular catheterization, intra-abdominal surgery, prolonged use of broad-spectrum antibiotics, immunosuppressive medications, hemodialysis, total parenteral nutrition (TPN), and extended intensive care unit (ICU) stays. Candida, one of the top three nosocomial bloodstream infections, [...] Read More
Tuğba Yanık-Yalçın and others
Ventriculoperitoneal shunts (VPSs) have been shown to be effective life-saving treatments for hydrocephalus. Nonetheless, the occurrence of VPS-related complications and infections necessitates close monitoring and care. Due to blood-brain and blood-cerebrospinal fluid (CSF) barriers, many anti-infective therapeutics have difficulty […] Read More
Yunus Kaygusuz and others
CGD patients are prone to recurrent, life-threatening infections caused by catalase-positive bacteria (i.e., Staphylococcus aureus, Burkholderia cepacia complex, Nocardia spp., and Serratia marcescens, and Aspergillus spp.). They can be diagnosed at any age, mostly under five. Nevertheless, they can be diagnosed in adulthood due to the incomplete penetrance and [...] Read More
Oğuz Usta and others
Human bocavirus 1 (HBoV1) was first identified in 2005 through the molecular screening of respiratory tract samples and linked to lower respiratory tract infections in children in Sweden. It is a member of the Parvoviridae family and has been associated with a range of clinical presentations […] Read More
Abdurrahman Kaya and others
Aspergillus spp. are ubiquitous and frequently inhaled by humans as spores in the natural environment and hospital settings. Despite this high frequency of exposure, aspergillosis is a rare disease in humans. Many Aspergillus spp. have been defined as causing infections, including Aspergillus fumigatus and Aspergillus flavus, among the most common [...] Read More
Zeynep Bilgiç and others
The use of antiretroviral therapy (ART) in individuals with the human immunodeficiency virus (HIV) has significantly increased their life expectancy. Nevertheless, an increase in the frequency of chronic diseases such as diabetes mellitus (DM), hypertension (HT), and cardiovascular disease (CVD) in this population with advancing age is expected. Also, they are at greater […] Read More
Hasan Selçuk Özger and others
Procalcitonin (PCT) is a biomarker frequently used in the diagnosis and prognosis of infection. The lack of optimum cut-off values and the high serum PCT levels in some non-infectious conditions restrict its clinical use. Therefore, PCT use is not recommended regardless of clinical parameters. This limitation in clinical use has led to PCT kinetic evaluations rather than predictions [...] Read More
Yusuf Ziya Demiroğlu and others
The hazards of sandfly viruses have been known for about 100 years. Sandfly fever viruses of the genus Phlebovirus in the Bunyaviridae family are endemic in Mediterranean, Middle Eastern, Northern African, and Western Asian countries. Sandfly viruses have been reported from Italy, Croatia, Spain, Cyprus, Iran, and Iraq. Read More
Mehmet Emirhan Işık and others
Infective endocarditis is the infection of the endocardial surfaces of the heart, including native valves, mural endocardium, or septal defects. Involvement of previously implanted prosthetic valves, intracardiac devices, or pacemakers are commonly predisposing risk factors for infective endocarditis. If left untreated, it is inevitably fatal due to complications such as congestive heart failure, stroke (...) Read More
Abdurrahman Kaya and others
Henoch-Schönlein purpura (HSP) is a systemic small-vessel vasculitis characterized by involvement in the skin, kidney, and gastrointestinal system. It is frequently seen in children, accounting for 90% of cases. HSP is less common in adults. Cutaneous involvement is the most common presentation, and in some cohorts, adult HSP is more severe and has worse [...] Read More
Ali Mert and others
Pyomyositis is a primary infection of skeletal muscle that does not result from a contiguous disease, is hematogenous in origin, and often results in abscess formation. Although pyomyositis is classically an infection in tropical regions, it is an emerging infection in temperate climates. Pyomyositis is frequently caused by aerobic Gram-positive and Gram-negative bacteria. Read More
Handan Alay and others
A 78-year-old male patient with diagnoses of diabetes, hypertension, and gout presented with fever, night sweats, weight loss, and back pain for the past two months. On physical examination, he had a body temperature of 37.5°C and tenderness on palpation in the thoracolumbar region. His white blood cell (WBC) count was [...] Read More
Merve Arslan and others
Infective endocarditis is a clinical condition that affects the endocardial surface of the heart, involving natural or prosthetic heart valves and intracardiac devices. It is a high-cost and high-mortality infectious disease with an increasing incidence and is more frequently diagnosed with advancing diagnostic methods. Along with well-defined cardiac (previous endocarditis, presence of intracardiac prosthetic materials, (...) Read More
Tuba Kuruoğlu and others
Reprocessing a disposable medical device in which sterility deteriorates without contact with the blood and body fluids is called “reprocessing.” If it is ready for use by being processed again for the same or another patient, it is named reuse. The increasing number of blood-borne diseases led to the broader use of disposable instruments. Cardiac catheters, (...) Read More
Gülşah Tunçer and others
Chronic hepatitis B (CHB) infection is a global health problem that the World Health Organization (WHO) reported 296 million individuals diagnosed with CHB, and 820,000 died worldwide in 2019. In our country, as per the Türkiye Viral Hepatitis Prevention and Control Program for 2018-2023, there have been 3.3 million patients with CHB infection in Türkiye. Read More
Mustafa Deniz and others
Eosinophilic cellulitis (EC) is a rare inflammatory skin condition with fewer than 200 documented cases in the medical literature. There are only a limited number of case reports available from our country. The prevalence and incidence of EC are unknown. The disease is characterized by pruritic, non-purulent, erythematous plaques (...) Read More