The Official Journal of the Turkish Society Of Clinical Microbiology and Infectious Diseases (KLİMİK)

Diagnosis

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Original Article / VOLUME 6, ISSUE 4, DECEMBER 2024

Comparison of a Commercial SARS-CoV-2 Rapid Antigen Test with Real-Time PCR

Muhammet Çağrı Yıldız and others

Real-time reverse transcriptase polymerase chain reaction (RT-PCR) is widely used to diagnose SARS-CoV-2. However, PCR tests need expensive equipment and qualified personnel, which makes them only used in high throughput and advanced laboratory settings. Improvements in SARS-CoV-2 diagnosis with easy, rapid, and cost-effective approaches […] Read More

Original Article / VOLUME 6, ISSUE 3, SEPTEMBER 2024

Associated Factors for Liver Fibrosis and Histological Activity Index in Treatment-Naïve HBeAg-Positive Chronic Hepatitis B Infection: Insights from a Retrospective Analysis

Kadir Görkem Güçlü and others

Hepatitis B virus (HBV) infection remains a significant public health issue globally. According to the latest data released by the World Health Organization (WHO) in July 2023, the number of individuals living with chronic hepatitis B (CHB) infection as of 2019 was reported as 296 million, with 820 million deaths attributed to cirrhosis and hepatocellular carcinoma [...] Read More

Original Article / VOLUME 6, ISSUE 3, SEPTEMBER 2024

Changes of Procalcitonin Kinetics According to Renal Clearance in Critically Ill Patients with Primary Gram-Negative Bloodstream Infections

Hasan Selçuk Özger and others

Procalcitonin (PCT) is a biomarker frequently used in the diagnosis and prognosis of infection. The lack of optimum cut-off values and the high serum PCT levels in some non-infectious conditions restrict its clinical use. Therefore, PCT use is not recommended regardless of clinical parameters. This limitation in clinical use has led to PCT kinetic evaluations rather than predictions [...] Read More

Brief Report / VOLUME 6, ISSUE 2, JUNE 2024

Rapid Bacterial Identification from Positive Blood Cultures by MALDI-TOF MS Following Short-Term Incubation on Solid Media

Mervenur Demir and Gülşen Hazırolan

Sepsis is a life-threatening infection with a mortality rate above 25%. Rapid identification of the microorganisms that cause bloodstream infections is important for choosing targeted and timely antimicrobial treatment. The implementation of matrix-assisted laser desorption ionization time-of-flight mass spectrometry (...) Read More

Brief Report / VOLUME 6, ISSUE 1, MARCH 2024

Comparison of the i-test COVID-19 Rapid Antigen Test with Real-Time Reverse Transcriptase PCR

Muhammet Çağrı Yıldız and others

Polymerase chain reaction (PCR) test is used in high-capacity laboratories in the diagnosis of COVID-19. On the other hand, rapid SARS-CoV-2 antigen tests require less technical expertise and laboratory capacity. Antigen tests, which are faster and cost-effective, are increasingly used in COVID-19 screening and diagnosis. This study aimed to compare the i-test (...) Read More

Review Article / VOLUME 5, ISSUE 4, DECEMBER 2023

Is There a Role for Dark Field Microscopy in the Diagnosis of Lyme Disease?
A Narrative Review

Uğur Önal and others

Lyme disease, also known as Lyme borreliosis, is the most common vector-borne disease in Europe and North America, caused by the spirochete Borrelia species, which can be transmitted through the bite of an infected black-legged tick. The Centers for Disease Control and Prevention (CDC) data on Lyme disease in the United States showed (...) Read More

Original Article / VOLUME 5, ISSUE 4, DECEMBER 2023

How Successful Are APRI and FIB-4 Scores in Predicting Liver Fibrosis in Chronic Hepatitis B Patients?

Deniz Gür-Altunay and Pınar Yürük-Atasoy

Hepatitis B virus (HBV) infection is an important public health problem worldwide. It is the most important cause of acute and chronic liver disease and hepatocellular cancer. Hepatitis B infection is diagnosed by the detection of HBsAg in the serum or plasma. Chronic hepatitis B (CHB) infection is defined as the persistence of (...) Read More

Original Article / VOLUME 5, ISSUE 4, DECEMBER 2023

Development of a Nanoplate-Based Digital PCR Test Method for Quantitative Detection of Human Adenovirus DNA

Yağmur Eylül Doğantürk and others

Human adenovirus (HAdV) is a non-enveloped, double-stranded DNA virus that causes self-limiting respiratory system infections, gastrointestinal tract infections, conjunctivitis, and meningitis. These infections are generally observed throughout the year with no seasonal distribution. Despite being self-limiting, HAdV infections (...) Read More

Original Article / VOLUME 5, ISSUE 2, JUNE 2023

Clinical Evaluation of Commercial HARDSON COVID-19 Antigen Rapid Test Kit for Routine COVID-19 Diagnosis

Reza Kamali Kakhki* and others

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is a respiratory disease agent belonging to the Betacoronavirus genera. The genome of the virus translates into four major structural proteins, including spike (S), nucleocapsid (N), membrane (M), and envelop (E) proteins. During the pandemic, huge numbers of mutations (...) Read More

Original Article / VOLUME 5, ISSUE 1, MARCH 2023

Ophthalmologic Examination and Echocardiography Should be the Essential Components of Candidemia Bundle

Çiğdem Erol and others

Candida species are major sources of morbidity and mortality in healthcare settings. These infections are predominantly connected with medical procedures. The five most prevalent pathogens- Candida albicans, Candida glabrata, Candida tropicalis, Candida parapsilosis, and Candida krusei – are responsible for (...) Read More

Original Article / VOLUME 2, ISSUE 1, APRIL 2020

Comparison of Coombs Gel Test with ELISA and Standard Tube Agglutination Tests Used in Serological Diagnosis of Brucellosis

Çiğdem Akalan Kuyumcu and others

Brucellosis is a zoonotic infectious disease caused by Gram-negative bacteria of the genus Brucella, which is transmitted from animals to humans by direct and indirect pathways. Brucellosis can be confused with various infectious and non-infectious diseases because of its nonspecific clinical signs and symptoms such as fever, sweating, Read More

Original Article / VOLUME 1, ISSUE 1, APRIL 2019

The effectiveness of the Culture for Dientamoeba fragilis from the Stool

Özgür Kurt and others

Dientamoeba fragilis is an intestinal protozoon classified among the flagellates inhabiting in the caecum and colonic lumen of humans. It has long been regarded as a commensal microorganism until when clinical reports indicate its association with gastrointestinal and dermatological case. Laboratory diagnosis of D. fragilis infections has long been limited to (...) Read More