antimicrobial therapy

Original Article / VOLUME 6, ISSUE 4, DECEMBER 2024

Clostridioides difficile Infections and Factors Associated with Recurrence

Sinan Çetin and Mediha Uğur

Clostridioides difficile is an anaerobic, Gram-positive, spore-forming bacteria found in the colon as part of the normal intestinal flora of a healthy individual. However, changes in the gut microbiota because of antibiotic use can lead to overgrowth of C. difficile and toxin […] Read More

Original Article / VOLUME 6, ISSUE 3, SEPTEMBER 2024

Changes of Procalcitonin Kinetics According to Renal Clearance in Critically Ill Patients with Primary Gram-Negative Bloodstream Infections

Hasan Selçuk Özger and others

Procalcitonin (PCT) is a biomarker frequently used in the diagnosis and prognosis of infection. The lack of optimum cut-off values and the high serum PCT levels in some non-infectious conditions restrict its clinical use. Therefore, PCT use is not recommended regardless of clinical parameters. This limitation in clinical use has led to PCT kinetic evaluations rather than predictions [...] Read More