Antimicrobial Stewardship
Kauke Bakari Zimbwe and others
Antimicrobial resistance (AMR) is declared one of humanity’s top ten global public health threats. AMR is associated with increased hospitalizations, extended hospital stays, readmissions, and a higher mortality risk. In 2019, 4.95 million deaths, including 1.27 million directly attributable, were associated with bacterial AMR. Sub-Saharan Africa has the highest all-age death rate [...] Read More
Mervenur Demir and others
The global increase in the rate of multi-drug resistant (MDR) bacterial infections in recent years is an important public health problem that limits the therapeutic options. The issue becomes particularly critical in cases of bloodstream infections (BSI) in which delay is associated with high mortality rates. Bacteria grown in blood cultures (BC) must be subcultured on the solid media (...) Read More
Bahar Madran and others
Surgical site infections (SSIs) are a significant global problem, and their burden increases with emerging antimicrobial resistance. Globally, around 12.3% of surgical patients suffer from SSIs annually, with higher rates in low-income countries (23.2%) compared to high-income countries (9.4%). Inappropriate antibiotic use not only escalates the rate of (...) Read More
Süda Tekin and others
Clostridioides difficile infections (CDIs) can present in various clinical forms, ranging from an asymptomatic carrier state to pseudomembranous colitis (PMC), and are recognized as one of the leading causes of diarrhea in healthcare centers. C. difficile-associated PMC is a life-threatening inflammatory bowel disease and may result in (...) Read More
Oğuz Evlice and others
The clinical spectrum of COVID-19 varies, ranging from asymptomatic infection to critical illness. The most commonly used tool for the classification of disease severity is the National Institute of Health (NIH) severity scale, which has four categories: mild, moderate, severe, and critical. Patients with moderate and severe clinical courses are followed up in wards, while those with (...) Read More
Anna-Arbana Makina and others
Over the last two decades, the rates of carbapenem-resistant (CR) pathogens have increased dramatically in Greek hospitals, with Klebsiella pneumoniae as the most worrisome representative (1). According to the recent European Annual Surveillance Report from the European Centre for Disease Prevention and Control (ECDC), Greece ranks first in Europe, with the highest percentage of (...) Read More