The Official Journal of the Turkish Society Of Clinical Microbiology and Infectious Diseases (KLİMİK)
Clostridioides difficile is an anaerobic, Gram-positive, spore-forming bacteria found in the colon as part of the normal intestinal flora of a healthy individual. However, changes in the gut microbiota because of antibiotic use can lead to overgrowth of C. difficile and toxin […] Read More
Ventriculoperitoneal shunts (VPSs) have been shown to be effective life-saving treatments for hydrocephalus. Nonetheless, the occurrence of VPS-related complications and infections necessitates close monitoring and care. Due to blood-brain and blood-cerebrospinal fluid (CSF) barriers, many anti-infective therapeutics have difficulty […] Read More
Antimicrobial resistance can lead to morbidity and mortality in serious infections. Therefore, antimicrobial resistance has been accepted as a global public health problem in the 21st century. Unnecessary and excessive use of drugs is a serious problem in our country as well as in the rest of the world. Unnecessarily used drugs play an important role (...) Read More
Healthcare workers were on the front line of the global effort against COVID-19. Thousands of physicians died from COVID-19 in many countries. In addition, difficulties in accessing personal protective equipment (PPE), lack of training, and workforce shortages have exposed the vulnerability of healthcare workers who desperately sought other options to protect (...) Read More
Urinary tract infections (UTIs) are seen in all age groups and are among the most frequent bacterial infections. Enterobacterales are the most common bacterial species that cause UTIs . Escherichia coli is the most common cause of both complicated UTIs (65%) and uncomplicated UTIs (75%). E. coli is followed by other Enterobacterales such as Klebsiella spp., Proteus spp., and Serratia spp. Resistance of urinary tract pathogens to (...) Read More
The clinical spectrum of COVID-19 varies, ranging from asymptomatic infection to critical illness. The most commonly used tool for the classification of disease severity is the National Institute of Health (NIH) severity scale, which has four categories: mild, moderate, severe, and critical. Patients with moderate and severe clinical courses are followed up in wards, while those with (...) Read More
Rational use of medicines (RUM) has been a concern worldwide for half a century, and is of great importance, given that almost half of all prescribed drugs are irrational. The irrational use of drugs can be disastrous and may cause adverse events, creating a (...) Read More
The COVID-19 pandemic emerged in Wuhan in December 2019 and spread rapidly all over the world. The number of cases worldwide reached a total of 150 million as of May 2021. While 14% of these cases required hospitalization with severe pneumonia (...) Read More
The first case of COVID-19 was reported on 10 March 2020 in Turkey. Various treatment options have been used in all countries because of the lack of proven treatment. Among these options, hydroxychloroquine (HQN) and azithromycin (AZ) combination is expected to treat Read More
Remdesivir is a novel nucleotide analogue antiviral drug with in vitro activity against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) (1). Food and Drug Administration (FDA) and Drug Controller General of India have authorized the emergency use for the treatment of COVID-19 under an Read More
The discovery of antibiotics has been a milestone for the treatment of infectious diseases. However, soon after antimicrobials came into use, it has been recognized that microorganisms become resistant. Antimicrobial resistance decreases the number of treatment options available in infectious diseases. Currently, antimicrobial resistance has become an issue […] Read More
Antibiotics are the most widely prescribed drugs in dentistry. Irrational use of antibiotics (IUA) is common in Turkey and other countries. However, IUA leads to the development of antibiotic resistance, which can significantly affect the quality health care and increase the cost. Emerging [...] Read More