The Official Journal of the Turkish Society Of Clinical Microbiology and Infectious Diseases (KLİMİK)

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Original Article / VOLUME 6, ISSUE 1, MARCH 2024

How Reliable is ChatGPT as a Novel Consultant in Infectious Diseases and Clinical Microbiology?

Gülşah Tunçer and Kadir Görkem Güçlü

Artificial intelligence models have influenced many branches of science in recent years. It is used in various departments of medicine. ChatGPT (Chat Generative Pre-trained Transformer) is a text-based artificial intelligence model developed by OpenAI. ChatGPT can be used in many areas of medicine, such as to generate medical text, answer medical questions, provide recommendations for diagnosis and treatment (...) Read More
Original Article / VOLUME 6, ISSUE 1, MARCH 2024

Infection Risk Prediction in Healthcare Settings: Lessons from COVID-19 Contact Tracing

Salih Keskin and others

Contact tracing has been recognized as a critical process in controlling infectious disease epidemics. Its objectives include early identification of potentially infectious cases and prevention of the emergence of new clusters. In the context of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection, in-hospital contact-tracing efforts (...) Read More
Original Article / VOLUME 6, ISSUE 1, MARCH 2024

Individualized High Dose Intravenous Anakinra Treatment in Cancer Patients with COVID-19 Associated Cytokine Storm: A Retrospective Controlled Study

Ramazan Çakmak and Murat Bektaş

Coronavirus disease 2019 (COVID-19) is a potentially life-threatening disease caused by SARS-CoV-2. Clinical findings of COVID-19 are ranged from asymptomatic to severe pneumoniae, acute respiratory distress syndrome, multiorgan failure and death. A severe COVID-19 course is associated with a higher inflammatory state (cytokine storm) due to the excessive release (...) Read More
Original Article / VOLUME 6, ISSUE 1, MARCH 2024

Predictors of Significant Histological Hepatic Abnormality in Treatment-Naive Patients Infected with HBeAg-Negative Chronic Hepatitis B

Gülşah Tunçer and others

Chronic hepatitis B (CHB)  infection is a global health problem that the World Health Organization (WHO) reported 296 million individuals diagnosed with CHB, and 820,000 died worldwide in 2019. In our country, as per the Türkiye Viral Hepatitis Prevention and Control Program for 2018-2023, there have been 3.3 million patients with CHB infection in Türkiye. Read More
Original Article / VOLUME 6, ISSUE 1, MARCH 2024

Knowledge and Attitudes of Patients About the Rational Use of Antibiotics

Pınar Korkmaz and others

Antimicrobial resistance can lead to morbidity and mortality in serious infections. Therefore, antimicrobial resistance has been accepted as a global public health problem in the 21st century. Unnecessary and excessive use of drugs is a serious problem in our country as well as in the rest of the world. Unnecessarily used drugs play an important role (...) Read More
Original Article / VOLUME 6, ISSUE 1, MARCH 2024

Detrimental Effects of Sterilization Types on Single-Use Coronary Angioplasty Catheters for Reuse: An Electron Microscopic Study

Tuba Kuruoğlu and others

Reprocessing a disposable medical device in which sterility deteriorates without contact with the blood and body fluids is called “reprocessing.” If it is ready for use by being processed again for the same or another patient, it is named reuse. The increasing number of blood-borne diseases led to the broader use of disposable instruments. Cardiac catheters, (...) Read More
Original Article / VOLUME 6, ISSUE 2, JUNE 2024

Prospective Clinical Follow-Up Results of Infective Endocarditis

Merve Arslan and others

Infective endocarditis is a clinical condition that affects the endocardial surface of the heart, involving natural or prosthetic heart valves and intracardiac devices.  It is a high-cost and high-mortality infectious disease with an increasing incidence and is more frequently diagnosed with advancing diagnostic methods. Along with well-defined cardiac (previous endocarditis, presence of intracardiac prosthetic materials, (...) Read More
Original Article / VOLUME 6, ISSUE 2, JUNE 2024

The Impact of Reporting the Same-Day Identification and Antibiotic Susceptibility Test Results on the Treatment of Bloodstream Infections

Mervenur Demir and others

The global increase in the rate of multi-drug resistant (MDR) bacterial infections in recent years is an important public health problem that limits the therapeutic options. The issue becomes particularly critical in cases of bloodstream infections (BSI) in which delay is associated with high mortality rates. Bacteria grown in blood cultures (BC) must be subcultured on the solid media (...) Read More
Original Article / VOLUME 6, ISSUE 2, JUNE 2024

Causative Microorganisms in Community-Acquired Urinary Tract Infections and Risk Factors for the Development of Infection with Extended-Spectrum β-Lactamase-Producing Species

Rüveyda Korkmazer and others

Urinary tract infection (UTI) affects approximately 150 million people worldwide every year and is encountered in all age groups. Escherichia coli, Klebsiella spp., group B streptococcus, and Enterococcus spp. are the most frequent species. The increase in antibiotic resistance rates among these agents leads to failures in empirical treatment and causes an increase in mortality, morbidity rates, and costs. Read More
Original Article / VOLUME 6, ISSUE 2, JUNE 2024

Antimicrobial Susceptibility of Various MRSA Clinical Isolates and the Impact of Glycopeptide MICs on Clinical and Microbiological Outcomes

Elif M. Sarıcaoğlu and Fügen Yörük

Staphylococcus aureus, particularly methicillin-resistant Staphylococcus aureus (MRSA), is a major cause of serious hospital and community-acquired infections and is associated with increased health care costs, prolonged antibiotic treatment and hospitalization, morbidity, and mortality. While glycopeptides (...) Read More
Original Article / VOLUME 6, ISSUE 2, JUNE 2024

The Incidence and Risk Factors of Early Periprosthetic Joint Infections

Zeynep Tekin-Taş and others

Hip and knee arthroplasties stand out as the most prevalent surgical interventions employed to address joint deformities, predominantly stemming from osteoarthritis associated with an aging population. In Turkey, a total of 34,240 hip arthroplasties and 81,109 knee arthroplasties were conducted in 2022. Meanwhile, in the United States of America (...) Read More
Original Article / VOLUME 6, ISSUE 2, JUNE 2024

The COVID-19 Vaccine Hesitancy Among Healthcare Workers: An Exploration of Hesitancy Reasons and Suggestions to Improve Vaccination Rates

Bahar Madran and others

The global impact of the coronavirus disease (COVID-19) pandemic has been profound, affecting billions of lives worldwide. As of June 13, 2024, the virus has infected approximately 704 million people and led to a staggering death toll of 7 million. In the fight against this devastating virus, the development and distribution of COVID-19 vaccines have been identified (...) Read More
Original Article / VOLUME 6, ISSUE 2, JUNE 2024

COVID-19 Vaccines and COVID-19 in People Living with HIV

Muhammed Fatih Karaşın and others

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), a strain of the coronavirus that causes COVID-19, spread rapidly around the world and was defined as a pandemic on March 12, 2020, by the World Health Organization. As of June 2023, more than 767 million cases were confirmed globally, along with 6.9 million deaths. Read More
Original Article / VOLUME 6, ISSUE 3, SEPTEMBER 2024

A New Biomarker Copeptin in Determining Disease Severity in COVID-19

Pınar Korkmaz and others

Coronavirus disease (COVID-19) remarkably impacted mortality rates and healthcare resources. The causative virus, SARS-CoV-2, is a member of the β family. Pulmonary manifestations of COVID-19 can range from asymptomatic infection to severe pneumonia and acute respiratory distress syndrome. Research regarding risk classifications [...] Read More
Original Article / VOLUME 6, ISSUE 3, SEPTEMBER 2024

The Efficacy of Glecaprevir/Pibrentasvir in Chronic Hepatitis C Patients and the Impact of the COVID-19 Pandemic: Multicenter Real-Life Data

Yunus Gürbüz and others

In 75-85% of cases of acute hepatitis C infection, the disease becomes chronic and carries a risk of developing liver failure and hepatocellular cancer. In its global hepatitis report published in 2017, the World Health Organization (WHO) reported that 71.1 (95% uncertainty interval [UI]: 62.1-79.0 million) million people were chronically infected with the hepatitis C virus [...] Read More
Original Article / VOLUME 6, ISSUE 3, SEPTEMBER 2024

Changes of Procalcitonin Kinetics According to Renal Clearance in Critically Ill Patients with Primary Gram-Negative Bloodstream Infections

Hasan Selçuk Özger and others

Procalcitonin (PCT) is a biomarker frequently used in the diagnosis and prognosis of infection. The lack of optimum cut-off values and the high serum PCT levels in some non-infectious conditions restrict its clinical use. Therefore, PCT use is not recommended regardless of clinical parameters. This limitation in clinical use has led to PCT kinetic evaluations rather than predictions [...] Read More
Original Article / VOLUME 6, ISSUE 3, SEPTEMBER 2024

Temporal Dynamics of Hepatitis B Infection and Relation of Childhood Vaccination Program in Türkiye: A Longitudinal Study

Okan Derin

Hepatitis B is an important global infectious disease. With its high prevalence and serious complications, such as liver cirrhosis, hepatocellular cancer, and death, controlling and monitoring hepatitis B is of paramount importance. In this context, the Global Burden of Disease (GBD) study dataset is an important resource for analyzing the prevalence[...] Read More
Original Article / VOLUME 6, ISSUE 3, SEPTEMBER 2024

Associated Factors for Liver Fibrosis and Histological Activity Index in Treatment-Naïve HBeAg-Positive Chronic Hepatitis B Infection: Insights from a Retrospective Analysis

Kadir Görkem Güçlü and others

Hepatitis B virus (HBV) infection remains a significant public health issue globally. According to the latest data released by the World Health Organization (WHO) in July 2023, the number of individuals living with chronic hepatitis B (CHB) infection as of 2019 was reported as 296 million, with 820 million deaths attributed to cirrhosis and hepatocellular carcinoma [...] Read More
Original Article / VOLUME 6, ISSUE 3, SEPTEMBER 2024

Antimicrobial Use Among Outpatients at Benjamin Mkapa Hospital in Dodoma Central Zone of Tanzania: A Prospective Descriptive Study

Kauke Bakari Zimbwe and others

Antimicrobial resistance (AMR) is declared one of humanity’s top ten global public health threats. AMR is associated with increased hospitalizations, extended hospital stays, readmissions, and a higher mortality risk. In 2019, 4.95 million deaths, including 1.27 million directly attributable, were associated with bacterial AMR. Sub-Saharan Africa has the highest all-age death rate [...] Read More
Original Article / VOLUME 6, ISSUE 3, SEPTEMBER 2024

The Relationship of Carotid and Brachial Artery Wall Thickness Measurement with Cardiovascular Risk Scoring in Individuals Living with HIV

Zeynep Bilgiç and others

The use of antiretroviral therapy (ART) in individuals with the human immunodeficiency virus (HIV) has significantly increased their life expectancy. Nevertheless, an increase in the frequency of chronic diseases such as diabetes mellitus (DM), hypertension (HT), and cardiovascular disease (CVD) in this population with advancing age is expected. Also, they are at greater […] Read More