The Official Journal of the Turkish Society Of Clinical Microbiology and Infectious Diseases (KLİMİK)

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Original Article / VOLUME 5, ISSUE 1, MARCH 2023

Evaluation of Clinical Approach and Outcomes Staphylococcus aureus Bacteremia

Tuğba Yanık-Yalçın and others

Staphylococcus aureus colonizes the skin and mucosa of humans. Infections because of S. aureus can range from skin infections to potentially fatal conditions like pneumonia, sepsis, and endocarditis. S. aureus is a common cause of nosocomial and community-acquired bloodstream infections worldwide. Because of biofilm (...) Read More

Original Article / VOLUME 5, ISSUE 1, MARCH 2023

Ophthalmologic Examination and Echocardiography Should be the Essential Components of Candidemia Bundle

Çiğdem Erol and others

Candida species are major sources of morbidity and mortality in healthcare settings. These infections are predominantly connected with medical procedures. The five most prevalent pathogens- Candida albicans, Candida glabrata, Candida tropicalis, Candida parapsilosis, and Candida krusei – are responsible for (...) Read More

Original Article / VOLUME 4, ISSUE 4, DECEMBER 2022

Thyroid Dysfunction among the Patients with Critical COVID-19

Hande Özportakal and others

The world has been fighting against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) for more than two years, leading to more than 605 million cases and 6.4 million deaths as of September 11, 2022. Since the angiotensin-converting enzyme (ACE) is the functional receptor for SARS-CoV-2, predominantly expressed by the alveoli (...) Read More

Original Article / VOLUME 4, ISSUE 4, DECEMBER 2022

Analysis of the Prophylactic use of Hydroxychloroquine at the Beginning of the COVID-19 Pandemic Among Physicians

Mehmet Gökhan Gönenli and others

Healthcare workers were on the front line of the global effort against COVID-19. Thousands of physicians died from COVID-19 in many countries. In addition, difficulties in accessing personal protective equipment (PPE), lack of training, and workforce shortages have exposed the vulnerability of healthcare workers who desperately sought other options to protect (...) Read More

Original Article / VOLUME 4, ISSUE 4, DECEMBER 2022

Comparison of CURB-65 Pneumonia Severity Score, Quick COVID-19 Severity Index, and Brescia-COVID Respiratory Severity Scale in Emergently Hospitalized COVID-19 Patients with Pneumonia

İbrahim Toker and others

Coronavirus disease 2019 (COVID-19) occurred with different levels of severity, and different criteria for hospitalizations were suggested, considering risk factors for poor outcomes, such as advanced age, comorbidities, lymphopenia, and high C-reactive protein (CRP) levels. The most severe complication of COVID-19 is viral pneumonia, which is often manifested by diffuse bilateral lung (...) Read More

Original Article / VOLUME 4, ISSUE 4, DECEMBER 2022

Prevalence of Fosfomycin Resistance Among Enterobacterales Isolates in A Tertiary Care Hospital from Turkey

Yeliz Tanrıverdi-Çaycı and others

Urinary tract infections (UTIs) are seen in all age groups and are among the most frequent bacterial infections. Enterobacterales are the most common bacterial species that cause UTIs . Escherichia coli is the most common cause of both complicated UTIs (65%) and uncomplicated UTIs (75%). E. coli is followed by other Enterobacterales such as Klebsiella spp., Proteus spp., and Serratia spp. Resistance of urinary tract pathogens to (...) Read More

Original Article / VOLUME 4, ISSUE 4, DECEMBER 2022

Stenotrophomonas maltophilia Bacteremia: From Diagnosis to Treatment

Pınar Aysert-Yıldız and others

Stenotrophomonas maltophilia is an aerobic, non-fermentative, Gram-negative bacterium widespread in aquatic environments and soil. It has an inherent ability to adhere to abiotic surfaces and forms biofilms. It is usually considered to be a commensal and a low-grade pathogen. However, it can cause severe infections in the immunocompromised and debilitated (...) Read More

Original Article / VOLUME 4, ISSUE 4, DECEMBER 2022

Prospective Evaluation of Infections in Geriatric Patients in Intensive Care Units

Hasan Naz and others

Nosocomial infections (NIs) constitute a major health issue in terms of morbidity, high mortality, prolonged hospitalization, and increased costs of direct patient care. While beds in intensive care units (ICUs) constitute less than 10% of all hospital beds, more than 20% of all NIs develop in the ICU. The human lifespan has been prolonged (...) Read More

Original Article / VOLUME 4, ISSUE 4, DECEMBER 2022

Evaluation of Blood Stream and Biliary Tract Infections Related to Percutaneous Transhepatic Cholangiography and Prophylaxis Given in Patients with Malignancy

Halime Araz and others

Percutaneous transhepatic cholangiography (PTC) is an invasive procedure used in patients with obstructive jaundice in the progress of some malignancies to reduce bilirubin levels, improve liver functions, prolong survival and enable other treatments. The procedure is critical because of its potential complications. The most common (...) Read More

Original Article / VOLUME 4, ISSUE 3, SEPTEMBER 2022

Maternal Stress and Neonatal Nutrition during the COVID-19 Era

Alara Altıntaş and others

COVID-19 has been the main focus of the world since the beginning of 2020. The virus has infected over 180 million people and caused about 6 million deaths worldwide up to February of 2022. With its rapid spread, the new coronavirus posed enormous economic, environmental, and social challenges together with health threats to the entire (...) Read More

Original Article / VOLUME 4, ISSUE 3, SEPTEMBER 2022

The Effect of the Pandemic on Antifungal Use: What Has Changed?

Vildan Avkan-Oğuz and others

Before coronavirus disease 2019 (COVID-19), antimicrobial stewardship (AMS) programs were essential for managing multidrug-resistant Gram-negative bacterial infections. In contrast, antifungal stewardship (AFS) programs were uncommon as a component of AMS. During the COVID-19 pandemic, both AMS and AFS programs have lost (...) Read More

Original Article / VOLUME 4, ISSUE 3, SEPTEMBER 2022

Cognitive Assessment of Young Adults Before and After Initiation of Combination Antiretroviral Therapy

Özlem Gül and others

The presence of cognitive disorders in the human immunodeficiency virus (HIV) infected individuals has been known for a long time. A complete neuropsychological evaluation method is a gold standard for diagnosing HIV-related cognitive impairment (HAND). However, such tests require specially trained personnel and specialized centers, and testing takes a long time. Montreal Cognitive (...) Read More

Original Article / VOLUME 4, ISSUE 3, SEPTEMBER 2022

Gardnerella vaginalis: Is it an Underestimated Cause of Urinary Symptoms in Males?

Mert Kılıç and others

Gardnerella vaginalis is an anaerobic, gram-negative/variable, small, pleomorphic microorganism. The jury is still out about the clinical significance of G. vaginalis. It is the predominant microorganism in women with vaginosis and also can be isolated from a vaginal secretion of 40-50% of asymptomatic women . On the other hand, male genitourinary tract infections (...) Read More

Original Article / VOLUME 4, ISSUE 3, SEPTEMBER 2022

Risk Factors for Mortality in Patients with Stenotrophomonas maltophilia Bloodstream Infections in Immunocompetent Patients

Şirin Menekşe and others

Stenotrophomonas maltophilia is a Gram-negative, non-fermentative aerobic bacterium that infects patients, especially with severe comorbidities such as hematological malignancies. It is commonly found in the environment and hospital settings. The most common clinical presentations are pneumonia and bloodstream infections (...) Read More

Original Article / VOLUME 4, ISSUE 3, SEPTEMBER 2022

Novel SARS-CoV-2 Omicron variants in İstanbul; Rapid Preponderance of BA.2 and BA.5

Yeşim Tuyji-Tok and others

Severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) variants have been detected since the summer of 2020, and their critical association with viral load, transmissibility, and escape from the innate-vaccine immune response were demonstrated. Another new variant was identified (...) Read More

Original Article / VOLUME 4, ISSUE 3, SEPTEMBER 2022

Antibiotic Use among Patients Hospitalized with COVID-19 and Treated in Three Different Clinics

Oğuz Evlice and others

The clinical spectrum of COVID-19 varies, ranging from asymptomatic infection to critical illness. The most commonly used tool for the classification of disease severity is the National Institute of Health (NIH) severity scale, which has four categories: mild, moderate, severe, and critical. Patients with moderate and severe clinical courses are followed up in wards, while those with (...) Read More

Original Article / VOLUME 4, ISSUE 2, JUNE 2022

Factors Associated with Gram-Negative Bacteremia and Mortality in Neutropenic Patients with Hematologic Malignancies in a High-Resistance Setting

Caglayan Merve Ayaz and others

The number of patients with hematological malignancies (HMs) and those undergoing hematopoietic stem cell transplantation (HSCT) has been on rise during the last three decades. Febrile neutropenia (FN) is the most common complication in this specific patient group and requires urgent intervention. Bacteremia […] Read More

Original Article / VOLUME 4, ISSUE 2, JUNE 2022

Necrotizing Fasciitis: Evaluation of 85 Cases and Usage of LRINEC Score

Ebru Oruç and others

Necrotizing fasciitis (NF), one of the necrotizing soft tissue infections, is an infection that primarily involves subcutaneous adipose tissue, which consists of superficial fascia, vascular and neural structures, and involves in deep fascia and progresses with mortality. It may be difficult to differentiate (...) Read More

Original Article / VOLUME 4, ISSUE 2, JUNE 2022

HIV and SARS‐Cov‐2 Co-Infection: A Local Perspective

Heval Can Bilek and Aydın Deveci

In early December 2019, interstitial pneumonia of unknown origin emerged in Wuhan, the capital of China’s Hubei province. The pathogen was identified as a novel beta coronavirus called severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), and the disease caused by SARS-CoV-2 was later named (...) Read More