The Official Journal of the Turkish Society Of Clinical Microbiology and Infectious Diseases (KLİMİK)
Human immunodeficiency virus (HIV) remains a significant global health challenge with societal impacts. Despite a decline in the annual number of new cases worldwide, the incidence of HIV is on the rise in the Eastern Europe/Central Asia region, including Türkiye. With the introduction of new antiretroviral treatments (ARTs), HIV has transitioned from a […] Read More
Hepatitis B virus (HBV) infection remains a significant public health issue globally. According to the latest data released by the World Health Organization (WHO) in July 2023, the number of individuals living with chronic hepatitis B (CHB) infection as of 2019 was reported as 296 million, with 820 million deaths attributed to cirrhosis and hepatocellular carcinoma [...] Read More
In 75-85% of cases of acute hepatitis C infection, the disease becomes chronic and carries a risk of developing liver failure and hepatocellular cancer. In its global hepatitis report published in 2017, the World Health Organization (WHO) reported that 71.1 (95% uncertainty interval [UI]: 62.1-79.0 million) million people were chronically infected with the hepatitis C virus [...] Read More
The hazards of sandfly viruses have been known for about 100 years. Sandfly fever viruses of the genus Phlebovirus in the Bunyaviridae family are endemic in Mediterranean, Middle Eastern, Northern African, and Western Asian countries. Sandfly viruses have been reported from Italy, Croatia, Spain, Cyprus, Iran, and Iraq. Read More
The cover image is a bowl from the 13th century, decorated with enamel colors and gilding on the glaze, dating back to the Great Seljuks. It is exhibited in the Berlin State Museum. According to the Museum's registration information, [...] Read More
The use of antiretroviral therapy (ART) in individuals with the human immunodeficiency virus (HIV) has significantly increased their life expectancy. Nevertheless, an increase in the frequency of chronic diseases such as diabetes mellitus (DM), hypertension (HT), and cardiovascular disease (CVD) in this population with advancing age is expected. Also, they are at greater […] Read More
Hepatitis B is an important global infectious disease. With its high prevalence and serious complications, such as liver cirrhosis, hepatocellular cancer, and death, controlling and monitoring hepatitis B is of paramount importance. In this context, the Global Burden of Disease (GBD) study dataset is an important resource for analyzing the prevalence[...] Read More
Infective endocarditis is the infection of the endocardial surfaces of the heart, including native valves, mural endocardium, or septal defects. Involvement of previously implanted prosthetic valves, intracardiac devices, or pacemakers are commonly predisposing risk factors for infective endocarditis. If left untreated, it is inevitably fatal due to complications such as congestive heart failure, stroke (...) Read More
Pyomyositis is a primary infection of skeletal muscle that does not result from a contiguous disease, is hematogenous in origin, and often results in abscess formation. Although pyomyositis is classically an infection in tropical regions, it is an emerging infection in temperate climates. Pyomyositis is frequently caused by aerobic Gram-positive and Gram-negative bacteria. Read More
A 78-year-old male patient with diagnoses of diabetes, hypertension, and gout presented with fever, night sweats, weight loss, and back pain for the past two months. On physical examination, he had a body temperature of 37.5°C and tenderness on palpation in the thoracolumbar region. His white blood cell (WBC) count was [...] Read More
The Crimean–Congo hemorrhagic fever (CCHF) virus was first identified in 1944 in the Crimean Peninsula in Eastern Europe and subsequently in the Congo in 1956. It belongs to the genus Nairovirus from the family Bunyaviridae. It causes a severe disease which is spread to humans through an infected tick bite and/or contact with blood or tissue from infected humans or animals. Read More
Antimicrobial resistance (AMR) is declared one of humanity’s top ten global public health threats. AMR is associated with increased hospitalizations, extended hospital stays, readmissions, and a higher mortality risk. In 2019, 4.95 million deaths, including 1.27 million directly attributable, were associated with bacterial AMR. Sub-Saharan Africa has the highest all-age death rate [...] Read More
Procalcitonin (PCT) is a biomarker frequently used in the diagnosis and prognosis of infection. The lack of optimum cut-off values and the high serum PCT levels in some non-infectious conditions restrict its clinical use. Therefore, PCT use is not recommended regardless of clinical parameters. This limitation in clinical use has led to PCT kinetic evaluations rather than predictions [...] Read More
Coronavirus disease (COVID-19) remarkably impacted mortality rates and healthcare resources. The causative virus, SARS-CoV-2, is a member of the β family. Pulmonary manifestations of COVID-19 can range from asymptomatic infection to severe pneumonia and acute respiratory distress syndrome. Research regarding risk classifications [...] Read More
Henoch-Schönlein purpura (HSP) is a systemic small-vessel vasculitis characterized by involvement in the skin, kidney, and gastrointestinal system. It is frequently seen in children, accounting for 90% of cases. HSP is less common in adults. Cutaneous involvement is the most common presentation, and in some cohorts, adult HSP is more severe and has worse [...] Read More
