The Official Journal of the Turkish Society Of Clinical Microbiology and Infectious Diseases (KLİMİK)

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Comparison of a Commercial SARS-CoV-2 Rapid Antigen Test with Real-Time PCR
Original Article

Comparison of a Commercial SARS-CoV-2 Rapid Antigen Test with Real-Time PCR

Muhammet Çağrı Yıldız and others

Real-time reverse transcriptase polymerase chain reaction (RT-PCR) is widely used to diagnose SARS-CoV-2. However, PCR tests need expensive equipment and qualified personnel, which makes them only used in high throughput and advanced laboratory settings. Improvements in SARS-CoV-2 diagnosis with easy, rapid, and cost-effective approaches […] Read More

Intraventricular TigecyclineTherapy for Ventriculoperitoneal Shunt-Related Septic Shock Caused by Colistin-Resistant Klebsiella pneumoniae: A Case Report
Case Report

Intraventricular Tigecycline
Therapy for Ventriculoperitoneal Shunt-Related Septic Shock Caused by Colistin-Resistant Klebsiella pneumoniae: A Case Report

Tuğba Yanık-Yalçın and others

Ventriculoperitoneal shunts (VPSs) have been shown to be effective life-saving treatments for hydrocephalus. Nonetheless, the occurrence of VPS-related complications and infections necessitates close monitoring and care. Due to blood-brain and blood-cerebrospinal fluid (CSF) barriers, many anti-infective therapeutics have difficulty […] Read More

Predictive Role and Clinical Value of Serum Cytokines in COVID-19
Original Article

Predictive Role and Clinical Value of Serum Cytokines in COVID-19

Fatihan Pınarlık and others

COVID-19 is caused by SARS-CoV-2 from the Coronaviridae family, Orthocoronaviridae sub family, Betacoronavirus genus, and Sarbecovirus subfamily (1). Cytokines and chemokines have been essential in the immune response against coronaviruses (2). First reports investigating clinical features of COVID-19 showed that serum levels of interleukin (IL)-2, IL-7, IL-10, granulocyte colony-stimulating factor (GSCF), IP10 (CXCL10), [...] Read More

Cytomegalovirus Infections in Patients Diagnosed with Inflammatory Bowel Disease
Original Article

Cytomegalovirus Infections in Patients Diagnosed with Inflammatory Bowel Disease

Melike İnan-Hekimoğlu and others

Cytomegalovirus (CMV) is a DNA virus from the Herpesviridae family that can remain latent in the body for life after primary infection and reactivate and cause viral shedding, especially in cases of immunosuppression. In studies conducted in different patient groups from Türkiye, CMV seroprevalence was reported to be between 85-100%. CMV can affect […] Read More

Early Diagnosis of Candidemia in the Intensive Care Unit by Clinical and Molecular Methods: A Prospective Observational Study
Original Article

Early Diagnosis of Candidemia in the Intensive Care Unit by Clinical and Molecular Methods: A Prospective Observational Study

Khalis Mustafayev and others

Invasive Candida infections have increased significantly in recent years due to various risk factors, including invasive procedures, vascular catheterization, intra-abdominal surgery, prolonged use of broad-spectrum antibiotics, immunosuppressive medications, hemodialysis, total parenteral nutrition (TPN), and extended intensive care unit (ICU) stays. Candida, one of the top three nosocomial bloodstream infections, [...] Read More

Original Article

Isolation and Antibiotic Resistance Rates of Mycobacterium tuberculosis complex in Mycolor TK® System

Dilara Yıldırım and others

Tuberculosis (TB) is a common disease with high mortality and morbidity worldwide. Globally, an estimated 10.6 million people (95% uncertainty interval [UI]=9.9-11.4 million) developed TB in 2022, compared with 10.3 million in 2021 and 10.0 million in 2020. TB caused an estimated 1.30 million deaths worldwide in 2022 (95% UI=1.18-1.43 million). This was […] Read More

An Adult-Onset Chronic Granulomatous Disease Case with Hemophagocytic Lymphohistiocytosis Caused by Burkholderia and Aspergillus Infections
Case Report

An Adult-Onset Chronic Granulomatous Disease Case with Hemophagocytic Lymphohistiocytosis Caused by Burkholderia and Aspergillus Infections

Yunus Kaygusuz and others

CGD patients are prone to recurrent, life-threatening infections caused by catalase-positive bacteria (i.e., Staphylococcus aureus, Burkholderia cepacia complex, Nocardia spp., and Serratia marcescens, and Aspergillus spp.). They can be diagnosed at any age, mostly under five. Nevertheless, they can be diagnosed in adulthood due to the incomplete penetrance and [...] Read More

Letter to the Editor

Chikungunya Surge in Pakistan: A Call for Rapid Public Health Measures

Marium Amjad

As Pakistan recovers from its enduring battle with COVID-19, it remains grappling with an ongoing public health crisis driven by mosquito-borne diseases like malaria, dengue and chikungunya. For many years, these prevalent arboviral illnesses have posed serious health risks. However, following the outbreak of chikungunya in Karachi and other parts of the […] Read More

Impact of Needle-Free Connector and Prefilled Flushing Syringe Shortage on CLABSI Rates in Pediatric Intensive Care
Original Article

Impact of Needle-Free Connector and Prefilled Flushing Syringe Shortage on CLABSI Rates in Pediatric Intensive Care

İlker Devrim and others

The most common and serious complication of central venous catheter usage is central line–associated bloodstream infections (CLABSIs) in children and adults. Between 2011 and 2014, CLABSIs were the most frequently reported healthcare-associated illness among hospitals in the USA. Bloodstream infections associated with central lines are […] Read More

Cystic Echinococcosis Cases: A Retrospective Evaluation in a General Surgery Department
Original Article

Cystic Echinococcosis Cases: A Retrospective Evaluation in a General Surgery Department

Oruç Numan Gökçe and others

Cystic echinococcosis (CE), caused mainly by Echinococcus granulosus, is a parasitic disease common in Mediterranean countries such as Türkiye. Although it can occur anywhere in the body, it predominantly affects the liver. The disease is often asymptomatic; thus, cysts are often detected incidentally during imaging studies performed for other purposes. Read More

Amphotericin B Resistant Aspergillus spp.: Report of Two Cases
Case Report

Amphotericin B Resistant Aspergillus spp.: Report of Two Cases

Abdurrahman Kaya and others

Aspergillus spp. are ubiquitous and frequently inhaled by humans as spores in the natural environment and hospital settings. Despite this high frequency of exposure, aspergillosis is a rare disease in humans. Many Aspergillus spp. have been defined as causing infections, including Aspergillus fumigatus and Aspergillus flavus, among the most common [...] Read More